ZK Cancer Research
A Family Company
The Problem
Cancer Cachexia Must Be Treated as Early as the Cancer Recognized, but It Isn’t in Practice
At some point of tumor development, about 70% of patients will unintentionally lose body weight and
muscle mass (as shown in the picture to the right), the process being termed “cancer cachexia”. Once cachexia
develops, it makes treatment inefficient. In fact, many cancer patients (~30%) die due to cachexia and
not the tumor itself. In today’s medical practice, treatment of cachexia is insufficient partly because
(a) when recognized it is too late to effectively deal with it, and (b) no single medication is available
to ensure satisfactory results due to its multifactorial (some of them unknown) nature.
ZK Cancer Research is a family-owned biotechnological company which is testing the effects of a
series of organic molecules (ZKC compounds) on the prevention of cancer cachexia in suitable mouse models.
The goal is to eventually use the most effective and least toxic compound as an affordable add-on drug for
the early treatment of human cancer patients.